bookbashuk Chapter 722 Imo Selection
Chapter 722 Imo Selection
More than 60 kinds of artificial compound white blood cells have been made in the laboratory.
But, no one can fight.
None of the three major difficulties, identification of friend or foe, reproduction restrictions, and functional balance, have been completely solved.
But we are not standing still, everything has been solved a little bit.
In terms of identifying friend or foe, artificial compound white blood cells have been successfully mixed into the bodies of mice and have been coexisting with the immune system for a long time.
The technology adopted is mainly derived from the technical reserves of previous gastric cancer drugs, and the artificial compound white blood cells are made to have characteristics similar to those of cancer cells, so as to evade the pursuit of the immune system.
First, the type I MHC molecules on the surface of artificial white blood cells are reduced to the lowest level, allowing CD8+ cytotoxic T cells to turn a blind eye to them. At the same time, trace amounts of type I MHC molecules are retained to avoid triggering natural killer cell trapping. Adding a little bit of mutated genes for immune tolerance, you can basically do it with ease and run rampant in the mice!
Ling Yiyi is very excited about this technology. She proposes that toxic carcinoid bacteria can be created to easily penetrate human immunity, thereby obtaining powerful biochemical weapons.
Song He decisively deducted two credits from her, forced her to copy the laboratory rules ten times, refused to teach her relevant techniques, and drove her to continue studying the Ling bacteria from sand to soil.
This girl is becoming more and more dangerous and must be strictly controlled.
Although the artificial white blood cells can be mixed into the mice, they do not distinguish between friend and foe and will actively attack multiple organs of the mice.
The effect is quite horrifying, almost exactly what Ling Yiyi wants. Less than five hours after the artificial white blood cells are injected into the mouse, the mouse will scream and die violently. When the body is dissected, the internal organs are as rotten as a sponge, and the entire body is full of blood. It was bloody, as if it had been run over by a truck.
The first major difficulty, identification of friend or foe, has not yet been solved!
In terms of reproduction restrictions, Song He clearly knocked out multiple genes responsible for reproduction. However, after a large number of artificial white blood cells are injected into mice, there will always be a small number of white blood cells that mutate and divide into very deformed offspring.
The deformed offspring continued to divide, eventually triggering an overreaction of the mouse's immune system, and finally died suddenly!
In other words, there are always fish that occasionally slip through the net with the ability to reproduce due to mutations. The reason is not yet clear, and no solution has been found.
The second major difficulty, breeding restrictions, has not been solved yet!
In terms of functional balance, artificial white blood cells have been able to successfully secrete a variety of cytokines, such as IFN-α, IL-2, interleukin... However, the secretion is extremely unstable, the impurities are highly toxic, and the ability to clean up dead red blood cells is extremely poor!
The third major difficulty, functional balance, has not yet been solved!
In fact, Song He knows the general solution direction, and there are relevant descriptions in the thousands of pages of information provided by the system.
But the bad thing lies in the word "relevant". The information will list dozens or hundreds of ways. It only says that most of the ways are proven to be wrong, but does not say which ones are wrong. Anyway, they are all relevant. , try it slowly!
With no choice, Song He could only lead his team to eliminate avenues day by day, constantly narrowing the scope, hoping to get lucky one day and obtain a perfect artificial compound white blood cell.
He didn't dare to use the black technology blueprint. He wasn't stingy. He just didn't know what he was doing. The more he worked on it, the more confused he became. It would be bad if he overturned. Since there was no urgent need for the artificial white blood cell project, he should take his time and learn while doing it.
This feels a bit like doing intelligence work. Song He remembers that when he chatted with Lao Zhao last time, Lao Zhao said that the most troublesome part of intelligence analysis is identification. It is not difficult to collect massive intelligence information. What is difficult is to remove exaggeration and fabrication. false information and find the real information that hits the mark.
The boring experiments were carried out day by day, the mice died one sack after the other, and the valuable experimental reagents were used up in boxes after boxes.
In the repetitive and boring life, there are also some things that can change your mood.
For example, a letter from a distant friend.
At the beginning of the final review week, Song He received another big box containing letters. There were only a few letters, not as many as before. After all, he had not returned to Ruoqiang base for a long time, and many old friends chatted on WeChat.
The first letter came from Ningmo. High school students are not allowed to play with mobile phones, but they can still write letters.
[Brother Song, good news! Great news! I won the National Prize in Mathematics! First prize! 】
[Zhang Zhilei also won the first place in the country! We were both very lucky this time, and all the questions we placed in advance were correct! 】
[A total of 60 of us entered the national training team, and there will be two rounds of training and selection. In the end, only 6 people can participate in IMO. The next IMO is scheduled for June next year, just after we have finished the college entrance examination and before the results are released. The free time is IMO competition]
Song He was secretly stunned, this elimination rate is too scary!
High school students across the country selected some mathematical geniuses to participate in the competition. The competition ended with only 60 people left!
These 60 mathematical wizards actually had to fight for two more rounds to pick one out of ten, and only six were left in the end!
Song He had two reactions in his heart. One reaction was that he was complacent. After all, he would definitely be able to kill to the end. He could kill other people as easily as he killed a chicken. The other reaction was worry. Can Ning Mo and Zhang Zhilei kill to the end?
[I am writing to you this time because I have a favor that I want to ask you for]
[You are awesome at answering questions and have also done competition questions. Can you help Zhang Zhilei and I come up with some awesome questions? 】
[Don’t go beyond the syllabus, we know that you have already entered the ranks of mathematicians, but we don’t need such high-end knowledge to do IMO, just within the scope of the normal knowledge syllabus]
[There are several classmates in our team who come from wealthy families. Their families have spent a lot of money to hire professors from famous schools to make exclusive problem sets, which is equivalent to a secret weapon to help them train. If you can help us come up with some problems, we can make up for this gap.]
【Thank you! Thank you! 】
[Ningmo Zhang Zhilei and his wife extend their sincere greetings and wish Brother Song success in his work and a happy life! 】