bookbashuk Chapter 714 Clinical Trial Of Artificial Red Blood Cells
Chapter 714 Clinical Trial Of Artificial Red Blood Cells
Just after the midterm exam, the laboratory finally made a decisive breakthrough!
Three special enzymes were found and added in controlled proportions, allowing artificial red blood cells to be successfully transfused into common ABO blood types!
The clinical trial process began immediately, and 36 volunteers of various blood types were quickly recruited.
The volunteers are all extremely poor patients with blood diseases, such as sickle cell disease and thalassemia, who require life-long blood transfusions every four to six weeks. However, they are heavily in debt and cannot afford medical expenses, so they have been relying on local governments. Subsidies and charities barely survive.
Chenghuang Company offered preferential terms to help clear the debts borne by the volunteers and bear the living expenses during the experiment, provided that the volunteers cooperated with the long-term experiment.
The desperate volunteers decided to give it a try for a chance of survival!
At 8 o'clock on weekend evening, all members of Song He's team gathered in the conference room, waiting for the live broadcast of the clinical trial.
The atmosphere was very tense, everyone looked serious, and breathing could be heard in silence.
Soon, a picture popped up on the big screen.
In a clean white blood transfusion room, doctors and nurses wearing green masks stood all over the room, checking blood transfusion equipment.
After the examination, the doctors and nurses announced that it was normal, and then stood aside and waited with great seriousness.
Song He frowned. The atmosphere in the blood transfusion room was too heavy, almost like preparing for an injection of death.
Bah, bah, bah, don't think about unlucky things.
Must succeed!
After a moment of waiting, the two volunteers were taken into the blood transfusion room.
As soon as the volunteers appeared, there was an uproar in the conference room, and many people's expressions changed.
There was a man and a woman, both skinny and skinny, with sparse hair. The female volunteer was quite young and her face was just a little yellow. The male volunteer was middle-aged, with a scary bronze color on his face, his hands were covered with spots, and his eyes were dim. The whole body exudes a sinister atmosphere.
It just looks like... a half-decomposed corpse with body spots!
Lou Jinghui couldn't help but ask in a low voice, "What's going on with this male volunteer? Is this what he looks like if he has a blood disease?"
Lou Jinghui has been busy researching and developing lunar plants recently and has not seriously studied blood. He was deeply shocked by the horrific faces of the volunteers.
"Hemochromatosis." Song He explained, "Frequent blood transfusions can lead to excessive iron deposition. Few women, mostly men, have bronze or gray-black skin, blue-black pigment spots in the mouth, and liver function. Abnormalities and Diabetes Symptoms.”
Lou Jinghui muttered "What a shame" and said nothing.
"Dong dong dong!" There was a knock on the conference room door suddenly.
Fan Tao, who was sitting at the door, stood up, opened the door slightly, and immediately said hello to the dean and opened the door.
Xiang Xiaotong, who was dressed in dark formal clothes, entered the door. Everyone in the conference room shouted hello to the dean. She nodded and glanced at the big screen, then looked next to Song He. Lou Jinghui quickly stood up and gave up his seat.
"Just started?" Xiang Xiaotong sat down.
"Just starting." Song He nodded and introduced softly, "The male volunteer is Pang Anzhi, blood type O, thalassemia, 49 years old, living on subsistence allowance. The female volunteer Pang Anzhi, blood type AB, sickle cell disease ,22 years old."
"Are these names brother and sister? Is there such a big age difference?" Xiang Xiaotong was stunned.
"They are not brothers and sisters. They are from the same village. They are all from the An family, so they may be somewhat related." Song He said.
"What is the content of this experiment?"
"Inject 15 ml of artificial red blood cells." Song He said, "It will start in about three minutes."
The doctors and nurses opened the equipment, tested the large bag of blood originally intended for injection, and then tested the artificial red blood cells provided by Song He's team, and mixed the two.
After mixing, wait for a while and measure the condition of the mixed blood to confirm that there is no abnormality.
Blood transfusion begins!
Pang Anzhi received the blood transfusion first, with a very calm expression. After all, he received a blood transfusion every other month. He had experienced hundreds of similar processes in his life, and blood transfusions were as routine to him as going to a restaurant.
Soon, the blood transfusion was completed.
The atmosphere in the blood transfusion room and conference room was so solemn that Song He even held his breath. The dead mouse flashed before his eyes, and his heart was beating fast.
For a long time, Pang Anzhi still looked normal, and his heart rate, blood pressure and other data were completely normal.
The doctor asked Pang Anzhi if he had any bad feelings, and he shook his head.
Immediately afterwards, Pang Anzhi was pushed into the scanner, and the live broadcast screen changed into a scan of blood circulation.
The artificial red blood cells were labeled with isotopes and could be seen clearly under the machine scan. As Pang Anzhi's heart continued to pump blood, the blood continued to flow throughout his body. Some artificial red blood cells quickly spread throughout his body, including his limbs, internal organs, and head. Clear traces soon appeared all over.
The atmosphere in the conference room is a little more relaxed. It seems that the effect is not bad?
Immediately afterwards, female volunteer Pang Anxin also received a blood transfusion.
Unlike Pang Anzhi, who was calm, Pang Anzhi was quite nervous. Her heart rate soared before the injection started. The doctor had to calm her down and hesitated for a long time before giving the injection.
After the blood transfusion was completed, Pang Anxin's heart rate soared crazily!
Her face changed, and she even complained that her chest was tight and weak!
Song He rubbed his hands nervously. The atmosphere in the conference room was high-pressure, and everyone was staring at the big screen.
The doctors and nurses were a little flustered and prepared to conduct a detailed examination on her, until an old doctor stood up, looked at the data displayed on the instrument, and smiled at Pang Anxin.
"No problem, the effect is very good."
After the old doctor finished speaking, Pang Anxin's physical data quickly improved and dropped to normal values. He was pushed into the scanning machine to check the trajectory of artificial red blood cells, which were spread throughout the body.
In the conference room, all members of Song He's team breathed a sigh of relief. There was no danger, and the microinjection experiment was successful!
"Pang Anzhi's mental quality is not good." Song He let go and smiled, "I was shocked when her heart rate went up. It was her who was frightened. Look at how calm Pang Anzhi is."
"Maybe because of age." Xiang Xiaotong said.
"Age?" Song He was startled and nodded, "Middle-aged people are more calm than young people."
"It's not that he is calm." Xiang Xiaotong looked at Pang Anzhi, who had an indifferent gaze in the corner of the screen. "A person who has been tortured by the disease for nearly fifty years has a numb attitude towards life and life. But An Xin is still young and still has an attitude towards life. There is hope.”
Song He was thoughtful for a moment and said, "Teacher, you are very thoughtful."
The microinjection experiment of the first two volunteers was declared a success, and the remaining 34 volunteers also completed the injections intensively within two days.
There were no adverse reactions, the physical examination results were all normal, and the situation was excellent!
After the news spread, more volunteers signed up, and the number of people participating in clinical trials quickly reached more than 300 people.
The transfusion dose of artificial red blood cells gradually increased, from tens of ml, to 100 ml, and then to 200, 300, and 400 ml!
Everything went well, the volunteers had no adverse reactions, their physical indicators even improved slightly, and the quality of the artificial red blood cells was fully tested!
The only pity is that most of the volunteers are patients with blood diseases, and there are currently no healthy people participating in clinical trials.
It doesn't matter, there are still rich people who can use it.
Song He released the news to various channels that there is an internal auction for quotas for red blood cell exchange transfusion to extend life span. The number is limited, so hurry up if you want to buy!